Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock

Persistent hyperlactatemia during septic shock is multifactorial. Hypoperfusion-related anaerobic production and adrenergic-driven aerobic generation together with impaired lactate clearance have been implicated. An excessive adrenergic response could contribute to persistent hyperlactatemia and adr...

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Autores:
Rebolledo, Rolando A.
Ospina Tascón, Gustavo Adolfo
Bakker, Jan
Kattan, Eduardo
Castro, Ricardo
Achurra, Pablo
Jarufe, Nicolás P.
Gomez, Jussara
Soto, Dagoberto
Tapia, Pablo J.
Hernández, Glenn P.
Bruhn, Alejandro R.
Luengo, Cecilia
Alegría, Leyla
Tipo de recurso:
Article of investigation
Fecha de publicación:
2016
Institución:
Universidad ICESI
Repositorio:
Repositorio ICESI
Idioma:
eng
OAI Identifier:
oai:repository.icesi.edu.co:10906/81644
Acceso en línea:
http://hdl.handle.net/10906/81644
http://dx.doi.org/10.1186/s13054-016-1419-x
Palabra clave:
Medical sciences
Lactate
Dexmedetomidine
Ciencias socio biomédicas
Esmolol
Dexmedetomidina
Lactatos
Rights
openAccess
License
https://creativecommons.org/licenses/by-nc-nd/4.0/