Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock

Persistent hyperlactatemia during septic shock is multifactorial. Hypoperfusion-related anaerobic production and adrenergic-driven aerobic generation together with impaired lactate clearance have been implicated. An excessive adrenergic response could contribute to persistent hyperlactatemia and adr...

Full description

Autores:

Rebolledo, Rolando A.
Ospina Tascón, Gustavo Adolfo
Bakker, Jan
Kattan, Eduardo
Castro, Ricardo
Achurra, Pablo
Jarufe, Nicolás P.
Gomez, Jussara
Soto, Dagoberto
Tapia, Pablo J.
Hernández, Glenn P.
Bruhn, Alejandro R.
Luengo, Cecilia
Alegría, Leyla

Tipo de recurso:

Article of investigation

Fecha de publicación:

2016

Institución:

Universidad ICESI

Repositorio:

Repositorio ICESI

Idioma:

eng

OAI Identifier:

oai:repository.icesi.edu.co:10906/81644

Acceso en línea:

http://hdl.handle.net/10906/81644
http://dx.doi.org/10.1186/s13054-016-1419-x

Palabra clave:

Medical sciences
Lactate
Dexmedetomidine
Ciencias socio biomédicas
Esmolol
Dexmedetomidina
Lactatos

Rights

openAccess

License

https://creativecommons.org/licenses/by-nc-nd/4.0/