Development of an Indole-Amide-Based Photoswitchable Cannabinoid Receptor Subtype 1 (CB1R) “Cis-On” Agonist

Activation of the human cannabinoid receptor type 1 (hCB1R) with high spatiotemporal control is useful to study processes involved in different pathologies related to nociception, metabolic alterations, and neurological disorders. To synthesize new agonist ligands for hCB1R, we have designed differe...

Full description

Autores:

Ramírez Rivera, Yesid Andres
Rodríguez Soacha, Diego A
Steinmüller, Sophie AM
Işbilir, Ali
Fender, Julia
Deventer, Marie H
Tutov, Anna
Sotriffer, Christoph
Stove, Christophe P
Lorenz, Kristina
Lohse, Martín J
Hislop, James N
Decker, Michael

Tipo de recurso:

Article of journal

Fecha de publicación:

2022

Institución:

Universidad ICESI

Repositorio:

Repositorio ICESI

Idioma:

eng

OAI Identifier:

oai:repository.icesi.edu.co:10906/104318

Acceso en línea:

http://repository.icesi.edu.co/biblioteca_digital/handle/10906/104318
https://doi.org/10.1021/acschemneuro.2c00160

Palabra clave:

photorimonabant
optical control
photopharmacology
CB1 agonist
G-protein-coupled
receptor
diazocine
Agonists
Receptors
Ligands
Azobenzene
Assays

Rights

openAccess

License

https://creativecommons.org/licenses/by-nc-nd/4.0/