Human polymorphism at microRNAs and microRNA target sites

MicroRNAs (miRNAs) function as endogenous translational repressors of protein-coding genes in animals by binding to target sites in the 3? UTRs of mRNAs. Because a single nucleotide change in the sequence of a target site can affect miRNA regulation, naturally occurring SNPs in target sites are cand...

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Autores:

Tipo de recurso:

Fecha de publicación:

2007

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/27817

Acceso en línea:

https://doi.org/10.1073/pnas.0611347104
https://repository.urosario.edu.co/handle/10336/27817

Palabra clave:

Human evolution
Positive selection
Single-nucleotide polymorphism

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