Cross-reactivity between annexin A2 and Beta-2-glycoprotein I in animal models of antiphospholipid syndrome

Antiphospholipid syndrome (APS) affects coagulation and the brain by autoimmune mechanisms. The major antigen in APS is beta-2-glycoprotein I (?2-GPI) is known to complex with annexin A2 (ANXA2), and antibodies to ANXA2 have been described in APS. We measured these antibodies in mice with experiment...

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Autores:

Tipo de recurso:

Fecha de publicación:

2017

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/24279

Acceso en línea:

https://doi.org/10.1007/s12026-016-8840-8
https://repository.urosario.edu.co/handle/10336/24279

Palabra clave:

Beta2 glycoprotein 1
Immunoglobulin g
Lipocortin 2
Beta2 glycoprotein 1
Immunoglobulin g
Lipocortin 2
Phospholipid antibody
Animal experiment
Animal model
Animal tissue
Antiphospholipid syndrome
Article
Chemoluminescence
Controlled study
Cross reaction
Enzyme linked immunosorbent assay
Female
Immobilized metal affinity chromatography
Immune response
Immunization
Immunoblotting
Immunoprecipitation
Mouse
Nonhuman
Priority journal
Protein expression
Radioimmunoprecipitation
Animal
Antiphospholipid syndrome
Bagg albino mouse
Blood
Brain
Cross reaction
Disease model
Immunology
Animals
Annexin a2
Antiphospholipid syndrome
Beta 2-glycoprotein i
Brain
Cross reactions
Enzyme-linked immunosorbent assay
Female
Immunoglobulin g
Annexin
Anticardiolipin
Antiphospholipid syndrome
Autoantibodies
Autoimmune
Beta-2-glycoprotein
inbred balb c
animal
antiphospholipid
Antibodies
Disease models
Mice

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