3D structure and immunogenicity of Plasmodium falciparum sporozoite induced associated protein peptides as components of fully-protective anti-malarial vaccine

SIAP-1 and SIAP-2 are proteins which are implicated in early events involving Plasmodium falciparum infection of the Anopheles mosquito vector and the human host. High affinity HeLa and HepG2 cell binding conserved peptides have been previously identified in these proteins, i.e. SIAP-1 34893 ( 421KV...

Full description

Autores:
Tipo de recurso:
Fecha de publicación:
2011
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/23510
Acceso en línea:
https://doi.org/10.1016/j.bbrc.2011.11.039
https://repository.urosario.edu.co/handle/10336/23510
Palabra clave:
High activity binding peptide
Hla dr antigen
Major histocompatibility antigen class 2
Malaria vaccine
Protein
Recombinant protein
Siap 1 protein
Siap 2 protein
Unclassified drug
Alpha helix
Amino acid sequence
Animal experiment
Antibody titer
Aotus
Article
Controlled study
Dna binding motif
Enzyme linked immunosorbent assay
Hela cell
Immunofluorescence test
Immunogenicity
Liver cell
Mouse
Nonhuman
Plasmodium falciparum
Priority journal
Protein modification
Proton nuclear magnetic resonance
Sporozoite
Vaccine production
Western blotting
Amino acid sequence
Humans
Immunodominant epitopes
Malaria vaccines
Molecular sequence data
Peptides
Plasmodium falciparum
Protozoan proteins
Recombinant proteins
Sporozoites
Anopheles (genus)
Plasmodium falciparum
1h nmr
Anti-malarial vaccine
Mhc-ii
Plasmodium falciparum
Siap-1
Siap-2
subunit
Vaccines
Rights
License
Abierto (Texto Completo)