ABIN1 dysfunction as a genetic basis for lupus nephritis
The genetic factors underlying the pathogenesis of lupus nephritis associated with systemic lupus erythematosus are largely unknown, although animal studies indicate that nuclear factor (NF)-?B is involved. We reported previously that aknockin mouse expressinganin active form of ABIN1 (ABIN1[D485N])...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2013
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- eng
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/22476
- Acceso en línea:
- https://doi.org/10.1681/ASN.2013020148
https://repository.urosario.edu.co/handle/10336/22476
- Palabra clave:
- Immunoglobulin enhancer binding protein
Mitogen activated protein kinase
Toll like receptor
A20 binding inhibitor of immunoglobulin enhancer binding protein 1 gene
African american
Animal experiment
Animal model
Article
Controlled study
European american
Gene
Genotype
Immunocompetent cell
Lupus erythematosus nephritis
Mouse
Nonhuman
Pathophysiology
Priority journal
Single nucleotide polymorphism
Systemic lupus erythematosus
Animals
Dna-binding proteins
Fluorescent antibody technique
Humans
Kidney
Lupus nephritis
Mice
Nf-kappa b
single nucleotide
inbred c57bl
knockout
Mice
Mice
Polymorphism
- Rights
- License
- Abierto (Texto Completo)