p-Methoxyphenol: A potent and effective scavenger for solid-phase peptide synthesis

During the final step of t-Boc/Bzl, solid-phase peptide synthesis (SPPS)-protecting groups from amino acids (aa) side chains must be removed from the target peptides during cleavage from the solid support. These reaction steps involve hydrolysis with hydrogen fluoride (HF) in the presence of a nucle...

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Autores:

Tipo de recurso:

Fecha de publicación:

2020

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/22427

Acceso en línea:

https://doi.org/10.1002/psc.3251
https://repository.urosario.edu.co/handle/10336/22427

Palabra clave:

Cleavage
P-cresol
P-methoxyphenol
Scavenger
Solid-phase peptide synthesis
T-boc/bzl strategy

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