From NGS assembly challenges to instability of fungal mitochondrial genomes: A case study in genome complexity

The presence of repetitive or non-unique DNA persisting over sizable regions of a eukaryotic genome can hinder the genome's successful de novo assembly from short reads: ambiguities in assigning genome locations to the non-unique subsequences can result in premature termination of contigs and t...

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Autores:

Tipo de recurso:

Fecha de publicación:

2016

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/23762

Acceso en línea:

https://doi.org/10.1016/j.compbiolchem.2016.02.016
https://repository.urosario.edu.co/handle/10336/23762

Palabra clave:

Dna
Fungi
Gene encoding
Mitochondria
Nucleic acids
Screening
De novo assemblies
Dna secondary structures
Eukaryotic genome
Genome assembly
Mitochondrial genomes
Next-generation sequencing
Premature termination
Regions of interest
Genes
Fungal genome
Metabolism
Mitochondrion
Mitochondria
Dna secondary structure
Fungal mitochondria
Genome assembly
Next generation sequencing
Repetitive dna
fungal
Genome

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