Regulation of PfEMP1-VAR2CSA translation by a Plasmodium translation-enhancing factor

Pregnancy-associated malaria commonly involves the binding of Plasmodium falciparum-infected erythrocytes to placental chondroitin sulfate A (CSA) through the PfEMP1-VAR2CSA protein. VAR2CSA is translationally repressed by an upstream open reading frame. In this study, we report that the P. falcipar...

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Autores:

Tipo de recurso:

Fecha de publicación:

2017

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/22642

Acceso en línea:

https://doi.org/10.1038/nmicrobiol.2017.68
https://repository.urosario.edu.co/handle/10336/22642

Palabra clave:

Calpain
Chondroitin sulfate
Parasite antigen
Protozoal protein
Erythrocyte
Female
Gene expression regulation
Genetics
Human
Malaria falciparum
Metabolism
Open reading frame
Parasitology
Placenta
Plasmodium
Plasmodium falciparum
Pregnancy
Pregnancy complication
Protein degradation
Protein synthesis
Calpain
Chondroitin sulfates
Erythrocytes
Female
Gene expression regulation
Humans
Open reading frames
Placenta
Plasmodium
Plasmodium falciparum
Pregnancy
Protein biosynthesis
Proteolysis
Protozoan proteins
parasitic
protozoan
falciparum
plasmodium falciparum
Var2csa protein
Antigens
Malaria
Pregnancy complications

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