Confirmation of an association between rs6822844 at the IL2-IL21 region and multiple autoimmune diseases: Evidence of a general susceptibility locus

Objective. Autoimmune diseases often have susceptibility genes in common, indicating similar molecular mechanisms. Increasing evidence suggests that rs6822844 at the IL2-IL21 region is strongly associated with multiple autoimmune diseases in individuals of European descent. This study was undertaken...

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Autores:
Tipo de recurso:
Fecha de publicación:
2010
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/22955
Acceso en línea:
https://doi.org/10.1002/art.27222
https://repository.urosario.edu.co/handle/10336/22955
Palabra clave:
Interleukin 2
Interleukin 21
Allele
Argentina
Article
Autoimmune disease
Behcet disease
Case control study
Celiac disease
Colombia
Controlled study
Data analysis
Enteritis
Europe
Evaluation
Evidence based medicine
Genetic association
Genetic susceptibility
Human
Insulin dependent diabetes mellitus
Major clinical study
Priority journal
Rheumatoid arthritis
Single nucleotide polymorphism
Sjoegren syndrome
Statistical significance
Systemic lupus erythematosus
Turkey (bird)
Ulcerative colitis
Argentina
Autoimmune diseases
Case-control studies
Colombia
Genetic predisposition to disease
Genotype
Humans
Interleukin-2
Interleukins
Phenotype
Sjogren's syndrome
Turkey
type 1
rheumatoid
single nucleotide
systemic
Arthritis
Diabetes mellitus
Lupus erythematosus
Polymorphism
Rights
License
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