The ubiquitin specific protease-4 (USP4) interacts with the S9/Rpn6 subunit of the proteasome

The proteasome is the major non-lysosomal proteolytic machine in cells that, through degradation of ubiquitylated substrates, regulates virtually all cellular functions. Numerous accessory proteins influence the activity of the proteasome by recruiting or deubiquitylating proteasomal substrates, or...

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Autores:

Tipo de recurso:

Fecha de publicación:

2012

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/23511

Acceso en línea:

https://doi.org/10.1016/j.bbrc.2012.09.075
https://repository.urosario.edu.co/handle/10336/23511

Palabra clave:

Lysine
Proteasome
Proteinase
Ubiquitin
Ubiquitin specific protease 4
Unclassified drug
Article
Controlled study
Embryo
Enzyme binding
Enzyme specificity
Enzyme structure
Enzyme substrate
Enzyme substrate complex
Female
Human
Human cell
In vitro study
Priority journal
Protein domain
Protein function
Protein protein interaction
Protein subunit
Ubiquitination
Hek293 cells
Hela cells
Humans
Proteasome endopeptidase complex
Ubiquitin thiolesterase
Proteasome
S9/psmd11/rpn6
Ubiquitin specific protease 4 (usp4)
Ubiquitin-like domain
tertiary
Protein structure

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Abierto (Texto Completo)