ADGRL3 (LPHN3) variants predict substance use disorder

Genetic factors are strongly implicated in the susceptibility to develop externalizing syndromes such as attention-deficit/hyperactivity disorder (ADHD), oppositional defiant disorder, conduct disorder, and substance use disorder (SUD). Variants in the ADGRL3 (LPHN3) gene predispose to ADHD and pred...

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Autores:

Tipo de recurso:

Fecha de publicación:

2019

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/23388

Acceso en línea:

https://doi.org/10.1038/s41398-019-0396-7
https://repository.urosario.edu.co/handle/10336/23388

Palabra clave:

Adhesion g protein coupled receptor l3
Amphetamine derivative
Barbituric acid derivative
Cocaine
G protein coupled receptor
Genomic dna
Opiate
Psychedelic agent
Sedative agent
Unclassified drug
G protein coupled receptor
Receptor
Adhesion g protein coupled receptor l3 gene
Adolescent
Adult
Alcoholism
Article
Attention deficit disorder
Cannabis addiction
Child
Clinical assessment
Cohort analysis
Comorbidity
Controlled study
Demography
Disease predisposition
Family
Female
Gene
Gene locus
Genetic association
Genetic epidemiology
Genetic model
Genetic risk
Genetic variability
Human
Longitudinal study
Major clinical study
Male
Pharmacogenetic testing
Population based case control study
Prediction
Randomized controlled trial
Retrospective study
Tobacco dependence
Case control study
Drug dependence
Genetic predisposition
Genetics
Risk factor
Single nucleotide polymorphism
Young adult
Adult
Case-control studies
Female
Genetic predisposition to disease
Humans
Longitudinal studies
Male
Risk factors
Substance-related disorders
Young adult
single nucleotide
g-protein-coupled
human
peptide
Lphn3 protein
Polymorphism
Receptors
Receptors

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Abierto (Texto Completo)