High non-protective, long-lasting antibody levels in malaria are associated with haplotype shifting in MHC-peptide-TCR complex formation: a new mechanism for immune evasion

An effective malarial vaccine must contain multiple immunogenic, protection-inducing epitopes able to block and destroy the P. falciparum malaria parasite, the most lethal form of this disease in the world. Our strategy has consisted in using conserved peptides blocking parasite binding to red blood...

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Autores:

Tipo de recurso:

Fecha de publicación:

2006

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/25934

Acceso en línea:

https://doi.org/10.1016/j.biochi.2006.01.005
https://repository.urosario.edu.co/handle/10336/25934

Palabra clave:

Malaria vaccine
Immunogenic peptides
MHC II-peptide-TCR Complex
Long-lasting antibody

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