An N-terminal SIAH-interacting motif regulates the stability of the ubiquitin specific protease (USP)-19

The Ubiquitin Specific Protease-19 (USP19) regulates cell cycle progression and is involved in the cellular response to different types of stress, including the unfolded protein response (UPR), hypoxia and muscle atrophy. Using the unique N-terminal domain as bait in a yeast-two hybrid screen we hav...

Full description

Autores:

Tipo de recurso:

Fecha de publicación:

2013

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/23513

Acceso en línea:

https://doi.org/10.1016/j.bbrc.2013.02.094
https://repository.urosario.edu.co/handle/10336/23513

Palabra clave:

Seven In Absentia Homolog 1
Seven In Absentia Homolog 2
Ubiquitin
Ubiquitin specific protease 19
Unclassified drug
Amino terminal sequence
Article
Human
Human cell
Priority journal
Protein protein interaction
Protein stability
Ubiquitination
Unfolded protein response
Amino Acid Motifs
Computational Biology
Endopeptidases
Enzyme Stability
HEK293 Cells
Hela Cells
Humans
Immunoprecipitation
Nuclear Proteins
Proteasome Endopeptidase Complex
Protein Binding
Protein Interaction Mapping
Proteolysis
Two-Hybrid System Techniques
Ubiquitin-Protein Ligases
Ubiquitination
Proteasomal degradation
SIAH degron
SIAH1 ligase
USP19
Western
Blotting

Rights

License

Abierto (Texto Completo)