Functionally relevant proteins in Plasmodium falciparum host cell invasion

A totally effective, antimalarial vaccine must involve sporozoite and merozoite proteins (or their fragments) to ensure complete parasite blocking during critical invasion stages. This Special Report examines proteins involved in critical biological functions for parasite survival and highlights the...

Full description

Autores:

Tipo de recurso:

Fecha de publicación:

2017

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/24286

Acceso en línea:

https://doi.org/10.2217/imt-2016-0091
https://repository.urosario.edu.co/handle/10336/24286

Palabra clave:

Apical membrane antigen 1
Cell transversal protein for ookinetes and spzs
Circumsporozoite protein 1
Erythrocyte binding antigen 140
Erythrocyte binding antigen 181
Erythrocyte binding antigen 75
Erythrocyte binding ligand
Erythrocyte binding ligand 1
Liver stage antigen 1
Liver stage antigen 3
Malaria vaccine
Merozoite apical erythrocyte binding ligand
Merozoite surface protein 1
Merozoite surface protein 10
Merozoite surface protein 2
Merozoite surface protein 4
Merozoite surface protein 7
Merozoite surface protein 9
Multidomain sporozoite surface protein 2
Parasite antigen
Serine repeat antigen 5
Sporozoite invasion associated protein 1
Sporozoite invasion associated protein 2
Sporozoite microneme protein essential for cell transversal 1
Sporozoite microneme protein essential for cell transversal 2
Sporozoite protein
Sporozoite threonine and asparagine rich protein
Thrombospondin related anonymous protein
Thrombospondin related sporozoite protein
Unclassified drug
Unindexed drug
Amino acid sequence
Cell invasion
Drug efficacy
Drug safety
Erythrocyte
Host parasite interaction
Human
Immunogenicity
Liver cell
Malaria
Merozoite
Nonhuman
Parasite immunity
Parasite survival
Plasmodium falciparum
Protein binding
Protein secondary structure
Protein structure
Protein tertiary structure
Review
Sporozoite
Vaccination
Animal
Drug design
Host pathogen interaction
Immunology
Malaria falciparum
Metabolism
Nuclear magnetic resonance spectroscopy
Parasitology
Plasmodium falciparum
X ray crystallography
Animals
Drug design
Erythrocytes
Hepatocytes
Host-pathogen interactions
Humans
Magnetic resonance spectroscopy
Malaria vaccines
Plasmodium falciparum
Chabp
Invasion-proteins
Malaria
Merozoite
Sporozoite
Vaccine
falciparum
protozoan
x-ray
Antigens
Crystallography
Malaria

Rights

License

Abierto (Texto Completo)