Biological and structural characteristics of the binding peptides from the sporozoite proteins essential for cell traversal (SPECT)-1 and -2

The sporozoite microneme proteins essential for cell traversal, SPECT-1 and SPECT-2, are considered attractive pre-erythrocytic immune targets due to the key role they play in crossing of the malaria parasite across the dermis and the liver sinusoidal wall, prior to invasion of hepatocytes. In this...

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Autores:

Tipo de recurso:

Fecha de publicación:

2011

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/22790

Acceso en línea:

https://doi.org/10.1016/j.peptides.2010.09.026
https://repository.urosario.edu.co/handle/10336/22790

Palabra clave:

Antibody
Circumsporozoite protein
Complement component c8
Perforin
Sporozoite proteins essential for cell traversal 1
Sporozoite proteins essential for cell traversal 2
Unclassified drug
Alpha helix
Article
Epitope mapping
Immunofluorescence
Molecular interaction
Plasmodium falciparum
Priority journal
Protein binding
Protein domain
Protein structure
Proton nuclear magnetic resonance
Amino acid sequence
Animals
Binding sites
Hela cells
Hepatocytes
Humans
Molecular sequence data
Peptides
Plasmodium falciparum
Protozoan proteins
Rabbits
Sporozoites
Oryctolagus cuniculus
Plasmodium falciparum
1h nmr
Antimalarial vaccine
High-activity binding peptides (habps)
Plasmodium falciparum
Spect-1
Spect-2

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