Immunological profile of a Plasmodium vivax AMA-1 N-terminus peptide-carbon nanotube conjugate in an infected Plasmodium berghei mouse model

We have covalently conjugated an N-terminus Plasmodium vivax apical membrane antigen-1 (AMA-1) peptide to functionalized carbon nanotubes (f-CNT). Immunological characterization of this molecular conjugate revealed that the immunogen-AMA-1 peptide was appropriately presented after being conjugated t...

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Autores:

Tipo de recurso:

Fecha de publicación:

2008

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/23447

Acceso en línea:

https://doi.org/10.1016/j.vaccine.2008.08.014
https://repository.urosario.edu.co/handle/10336/23447

Palabra clave:

Apical membrane antigen 1
Carbon nanotube
Drug carrier
Polyclonal antibody
Amino terminal sequence
Animal experiment
Animal model
Article
Bagg albino mouse
Conjugation
Controlled study
Drug delivery system
Drug structure
Female
Immune system
Immunogenicity
Malaria
Mouse
Nonhuman
Parasitemia
Plasmodium berghei
Plasmodium vivax
Priority journal
Alleles
Amino acid sequence
Animals
Cytokines
Drug delivery systems
Enzyme-linked immunosorbent assay
Female
Fluorescent antibody technique
Hla-dr antigens
Malaria
Malaria vaccines
Membrane proteins
Mice
Molecular sequence data
Nanotubes
Plasmodium berghei
Plasmodium vivax
Protozoan proteins
Apical membrane antigen 1 (ama-1)
Functionalized carbon nanotubes (f-cnt)
Synthetic vaccine delivery system
protozoan
mhc class ii
subunit
western
inbred balb c
electron
Antigens
Blotting
Genes
Mice
Microscopy
Vaccines

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