Fitting modified HRP-I peptide analogue 3D structure into HLA-DR molecules induces protection against Plasmodium falciparum malaria

Conserved, high-activity, red blood cell binding malaria peptide 6786, from the HRP-I protein, having a random 3D structure as determined by 1H-NMR, was non-immunogenic and non-protection inducing when used as an immunogen in Aotus monkeys. Modifications made in its amino acid sequence were thus per...

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Autores:

Tipo de recurso:

Fecha de publicación:

2005

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/25938

Acceso en línea:

https://doi.org/10.1016/j.biocel.2004.07.012
https://repository.urosario.edu.co/handle/10336/25938

Palabra clave:

Malaria
KAHRP-I
NMR
Structural calculations
HLA-DR

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