Genomic analyses reveal moderate levels of ploidy, high heterozygosity and structural variations in a Colombian isolate of Leishmania (Leishmania) amazonensis

Leishmania amazonensis is one of the causative agents of the different forms of cutaneous leishmaniasis present in Latin America. This species has been isolated from humans and animals (canine/feline) in some endemic regions of Colombia. Therefore, L. amazonensis is of great relevance at the clinica...

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Autores:
Tipo de recurso:
Fecha de publicación:
2020
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/23719
Acceso en línea:
https://doi.org/10.1016/j.actatropica.2019.105296
https://repository.urosario.edu.co/handle/10336/23719
Palabra clave:
Epidemiology
Genetic variation
Genomics
Heterozygosity
Leishmaniasis
Parasite
Ploidy
Aneuploidy
Article
Chromosome variant
Colombia
Controlled study
Copy number variation
Genetic variation
Genome analysis
Heterozygosity
Leishmania amazonensis
Nonhuman
Parasite development
Parasite survival
Parasite virulence
Phylogeny
Ploidy
Single nucleotide polymorphism
Species comparison
Whole genome sequencing
Colombia
Animalia
Leishmania amazonensis
Aneuploidy
Copy number variation
Diversity
Dna-seq
Genome sequencing
L
Amazonensis
Parasites
Rights
License
Abierto (Texto Completo)