Designing and optimizing new antimicrobial peptides: all targets are not the same

Because the resistance of microorganisms to the available antibiotics is a growing healthcare problem worldwide, the search for new antimicrobial peptides (AMPs) that provide useful therapeutic options has been increasing in importance. Many initial candidates have had to be discarded after having a...

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Autores:
Tipo de recurso:
Fecha de publicación:
2019
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/23781
Acceso en línea:
https://doi.org/10.1080/10408363.2019.1631249
https://repository.urosario.edu.co/handle/10336/23781
Palabra clave:
Antifungal agent
Antiinflammatory agent
Antineoplastic agent
Antiparasitic agent
Antivirus agent
Polypeptide antibiotic agent
Amino acid composition
Amino acid sequence
Antibacterial activity
Antibiofilm activity
Antibiotic resistance
Antifungal activity
Antiinflammatory activity
Antimicrobial activity
Antineoplastic activity
Antiparasitic activity
Antiviral activity
Bacterial membrane
Drug cost
Drug design
Drug selectivity
Drug stability
Human
Hydrophobicity
Nonhuman
Priority journal
Protein structure
Review
Saccharomyces cerevisiae
Static electricity
Structure activity relation
Antimicrobial activity
Antimicrobial peptides
Hemolytic activity
Minimum inhibitory concentration (mic)
Sar study
Selectivity
Rights
License
Abierto (Texto Completo)