Evaluating the anti-leishmania activity of Lucilia sericata and Sarconesiopsis magellanica blowfly larval excretions/secretions in an in vitro model

Leishmaniasis is a vector-borne disease caused by infection by parasites from the genus Leishmania. Clinical manifestations can be visceral or cutaneous, the latter mainly being chronic ulcers. This work was aimed at evaluating Calliphoridae Lucilia sericata- and Sarconesiopsis magellanica-derived l...

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Autores:

Tipo de recurso:

Fecha de publicación:

2018

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/23674

Acceso en línea:

https://doi.org/10.1016/j.actatropica.2017.09.033
https://repository.urosario.edu.co/handle/10336/23674

Palabra clave:

Antileishmanial agent
Meglumine antimonate
Insect protein
Disease
Fly
Larva
Modeling
Parasite
Amastigote
Antiprotozoal activity
Article
Calliphoridae
Cell viability assay
Concentration (parameters)
Concentration response
Controlled study
Cytotoxicity
Excretion
Host cell
Human
Human cell
Ic50
In vitro study
Larva
Lc50
Leishmania panamensis
Leishmaniasis
Lucilia sericata
Macrophage
Microscopy
Nonhuman
Parasite load
Promastigote
Quantitative analysis
Resazurin assay
Sarconesiopsis magellanica
Secretion (process)
Survival index
U-937 cell line
Animal
Diptera
Drug effects
Larva
Leishmania
Parasitology
Calliphoridae
Leishmania panamensis
Lucilia sericata
Animals
Diptera
Insect proteins
Larva
Leishmania
Macrophages
Parasite load
Ic50
Larval excretion/secretion
Leishmania panamensis
Lucilia sericata
Sarconesiopsis magellanica
U937

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