Structural analysis of owl monkey MHC-DR shows that fully-protective malaria vaccine components can be readily used in humans

More than 50 years ago the owl monkey (genus Aotus) was found to be highly susceptible to developing human malaria, making it an excellent experimental model for this disease. Microbes and parasites' (especially malaria) tremendous genetic variability became resolved during our malaria vaccine...

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Autores:

Tipo de recurso:

Fecha de publicación:

2017

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/23518

Acceso en línea:

https://doi.org/10.1016/j.bbrc.2017.08.012
https://repository.urosario.edu.co/handle/10336/23518

Palabra clave:

HLA DRB1 antigen
Malaria vaccine
HLA antigen class 2
Malaria vaccine
Aotus
Article
Controlled study
Genetic variability
Human
Hydrophobicity
Immunofluorescence test
Immunogenicity
Malaria falciparum
Nonhuman
Plasmodium falciparum
Priority journal
Proton nuclear magnetic resonance
Static electricity
Vaccination
Western blotting
Animal
Antigen antibody reaction
Aotidae
Chemistry
Immunology
Animals
Antigen-Antibody Reactions
Aotidae
Histocompatibility Antigens Class II
Humans
Malaria Vaccines
Animal model
HLA-peptide binding
IMPIPS
Malarial-vaccine
MHC-DR

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