Influence of Variations in CCL3L1 and CCR5 on Tuberculosis in a Northwestern Colombian Population

We investigated the association of polymorphisms in CCR5, the major human immunodeficiency virus (HIV)-1 coreceptor, and copy number of its potent ligand CCL3L1 with tuberculosis in 298 individuals from Colombia. The CCR5-HHD haplotype, a known genetic determinant of increased susceptibility to HIV-...

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Autores:

Tipo de recurso:

Fecha de publicación:

2011

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/22374

Acceso en línea:

https://doi.org/10.1093/infdis/jir145
https://repository.urosario.edu.co/handle/10336/22374

Palabra clave:

CCL3L1 chemokine
Chemokine
Chemokine receptor CCR5
Macrophage inflammatory protein 1alpha
Membrane protein
Unclassified drug
Virus receptor
Acquired immune deficiency syndrome
Adult
Article
CCR5 gene
Colombia
Controlled study
DNA polymorphism
Female
Gene
Gene dosage
Genetic susceptibility
Genetic variability
Haplotype
Human
Human cell
Human immunodeficiency virus 1
Human immunodeficiency virus infection
Major clinical study
Male
Priority journal
Protein expression
Tuberculosis
Adult
Case-Control Studies
Colombia
Female
Gene Dosage
Haplotypes
Humans
Linkage Disequilibrium
Logistic Models
Male
Middle Aged
Tuberculosis
CCR5
Genetic
CC
Chemokines
Polymorphism
Receptors

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