A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy

Background: Electrocardiographic measures of left ventricular hypertrophy (LVH) are used as predictors of cardiovascular risk. We combined linkage and association analyses to discover novel rare genetic variants involved in three such measures and two principal components derived from them. Methods:...

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Autores:

Tipo de recurso:

Fecha de publicación:

2018

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/20386

Acceso en línea:

https://doi.org/10.1186/s12920-018-0339-9
https://repository.urosario.edu.co/handle/10336/20386

Palabra clave:

Chromosome 11
Chromosome 15
Dutchman
Exome Analysis
Gene
Gene Locus
Genetic Analysis
Genetic Association
Genetic Variability
Heart Left Ventricle Hypertrophy
Human
Limit Of Detection
Linkage Analysis
Major Clinical Study
Male
Map3K11 Gene
Microarray Analysis
Netherlands
Priority Journal
Whole Exome Sequencing
Cromosoma 11
Cromosoma 15
Enfermedades
Adult
Article
Female
Middle Aged
Cardiomegalia
Enfermedades cardiovasculares

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