Conserved high activity binding peptides from the Plasmodium falciparum Pf34 rhoptry protein inhibit merozoites in vitro invasion of red blood cells

Rhoptries are specialized secretory organelles found in all members of the genus Plasmodium whose proteins have been considered as promising vaccine candidates due to their involvement in cell invasion and the formation of the parasitophorous vacuole (PV). The Plasmodium falciparum Pf34 protein was...

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Autores:

Tipo de recurso:

Fecha de publicación:

2010

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/22785

Acceso en línea:

https://doi.org/10.1016/j.peptides.2010.07.009
https://repository.urosario.edu.co/handle/10336/22785

Palabra clave:

Adhesin
Antimalarial agent
High activity binding peptide 36051
High activity binding peptide 36053
High activity binding peptide 36055
High activity binding peptide 36056
Peptide derivative
Plasmodium falciparum pf34 protein
Protozoal protein
Unclassified drug
Amino acid sequence
Article
Cell invasion
Circular dichroism
Drug inhibition
Drug receptor binding
Erythrocyte
Human
Human cell
In vitro study
Merozoite
Plasmodium falciparum
Polymerase chain reaction
Priority journal
Protein interaction
Amino acid sequence
Animals
Erythrocytes
Humans
Membrane glycoproteins
Plasmodium falciparum
Protozoan proteins
Plasmodium falciparum
Detergent-resistant microdomains
Gpi-anchored
Peptides
Receptors
Vaccine

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