Unraveling the chromosome 17 patterns of FISH in interphase nuclei: An in-depth analysis of the HER2 amplicon and chromosome 17 centromere by karyotyping, FISH and M-FISH in breast cancer cells

Background: In diagnostic pathology, HER2 status is determined in interphase nuclei by fluorescence in situ hybridization (FISH) with probes for the HER2 gene and for the chromosome 17 centromere (CEP17). The latter probe is used as a surrogate for chromosome 17 copies, however chromosome 17 (Chr17)...

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Autores:

Tipo de recurso:

Fecha de publicación:

2014

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/23559

Acceso en línea:

https://doi.org/10.1186/1471-2407-14-922
https://repository.urosario.edu.co/handle/10336/23559

Palabra clave:

Epidermal growth factor receptor 2
Carrier protein
Dna binding protein
Dna topoisomerase (atp hydrolysing)
Dna topoisomerase ii alpha
Membrane protein
Tumor antigen
Amplicon
Article
Breast cancer cell line
Bt474 cell line
Centromere
Chromosome 11
Chromosome 17
Chromosome 8
Chromosome g band
Chromosome rearrangement
Chromosome translocation
Fluorescence in situ hybridization
Gene location
Gene mapping
Human
Human tissue
Interphase
Investigative procedures
Jimt 1 cell line
Karyotyping
Kpl4 cell line
Mcf 7 cell line
Mda mb231 cell line
Mda mb361 cell line
Multicolor fluorescence in situ hybridization
Oncogene
Oncogene neu
Polysome
Signal transduction
Skbr3 cell line
Stard3 gene
T47d cell line
Tnbc case cell line
Top2a gene
Triple negative breast cancer
Zr 75 1 cell line
Carcinoma
Cell nucleus
Centromere
Cytology
Fluorescence in situ hybridization
Gene translocation
Genetics
Interphase
Karyotyping
Metaphase
Procedures
Proto oncogene
Tumor cell line
Carcinoma
Carrier proteins
Cell nucleus
Centromere
Dna-binding proteins
Humans
Interphase
Karyotyping
Membrane proteins
Metaphase
Triple negative breast neoplasms
Breast cancer
Cep17
Chromosomal rearrangements
Chromosome 17
Her2
M-fish
Polysomy
Stard3
Top2a
human
type ii
tumor
neoplasm
genetic
fluorescence
erbb-2
human
pair 17
Stard3 protein
Antigens
Cell line
Chromosomes
Dna topoisomerases
Genes
In situ hybridization
Translocation

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