Bioenergetic and proteolytic defects in fibroblasts from patients with sporadic Parkinson's disease

Background: Parkinson's disease (PD) is a complex disease and the current interest and focus of scientific research is both investigating the variety of causes that underlie PD pathogenesis, and identifying reliable biomarkers to diagnose and monitor the progression of pathology. Investigation...

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Autores:

Tipo de recurso:

Fecha de publicación:

2014

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/18721

Acceso en línea:

http://repository.urosario.edu.co/handle/10336/18721

Palabra clave:

Extracellular Flux Analyzer
Fibroblasts
Parkinson'S Disease
Rotenone
Ubiquitin Proteasome System
Dopamine Receptor Stimulating Agent
Levodopa
Rotenone
Superoxide
Ubiquitin
Acidification
Adult
Apoptosis
Article
Bioenergy
Cell Death
Cell Viability
Chaperone-Mediated Autophagy
Clinical Article
Clinical Practice
Controlled Study
Dopaminergic Nerve Cell
Energy Yield
Enzyme Active Site
Female
Fibroblast
Glycolysis
Human
Lipid Peroxidation
Male
Middle Aged
Mitochondrial Respiration
Nerve Degeneration
Oxidation Reduction Potential
Oxidative Phosphorylation
Oxygen Consumption
Parkinson Disease
Priority Journal
Protein Quality
Skin Biopsy
Western Blotting
Extracellular Flux Analyzer
Fibroblasts
Parkinson'S Disease
Rotenone
Ubiquitin Proteasome System
Adenosine Triphosphate
Apoptosis
Autophagy
Case-Control Studies
Energy Metabolism
Female
Fibroblasts
Homeostasis
Humans
Male
Middle Aged
Mitochondria
Oxygen Consumption
Parkinson Disease
Proteasome Endopeptidase Complex
Rotenone
Superoxides
Ubiquitin
Uncoupling Agents
Enfermedad de Parkinson
Neuronas dopaminérgicas
Fibroblastos

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Abierto (Texto Completo)