Characterization of Plasmodium falciparum integral membrane protein Pf25-IMP and identification of its red blood cell binding sequences inhibiting merozoite invasion in vitro

The identification of proteins present on the surface of Plasmodium falciparum-infected red blood cells as well as of free merozoites has been widely considered as one of the main areas of research in the development of an antimalarial vaccine due to their involvement in the parasite's pathogen...

Full description

Autores:
Tipo de recurso:
Fecha de publicación:
2008
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/22894
Acceso en línea:
https://doi.org/10.1110/ps.036251.108
https://repository.urosario.edu.co/handle/10336/22894
Palabra clave:
Amino acid
Leucylasparaginyllysyllysylthreonylvalylvalylarginyllysyl isoleucylalanylglutamylglycylleucylglycyltyrosylthreonylisoleucylvalyl phenylalanine
Membrane protein
Pf25 membrane protein
Tyrosyllysylthreonylalanylasparaginylglutamylasparaginylvalyllysyl leucylalanylserylserylleucylserylaspartylarginylleucylserylarginine
Unclassified drug
Article
Binding affinity
Controlled study
Erythrocyte
Gene
Genetic transcription
Human
Human cell
Immunofluorescence
Mal8p1.3 gene
Merozoite
Plasmodium falciparum
Priority journal
Protein analysis
Protein binding
Western blotting
Amino acid sequence
Animals
Base sequence
Binding sites
Chymotrypsin
Erythrocytes
Humans
Membrane proteins
Merozoites
Molecular sequence data
Molecular weight
Neuraminidase
Peptide fragments
Plasmodium falciparum
Protein binding
Protozoan proteins
Trypsin
Capra hircus
Plasmodium falciparum
Binding assay
Pf25-imp
Plasmodium falciparum
Red blood cell
Synthetic peptide
secondary
protozoan
genetic
drug
amino acid
cultured
tertiary
Cells
Dose-response relationship
Genes
Protein structure
Protein structure
Sequence homology
Transcription
Rights
License
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