Rosette-Disrupting Effect of an Anti-Plasmodial Compound for the Potential Treatment of Plasmodium falciparum Malaria Complications

The spread of artemisinin-resistant parasites could lead to higher incidence of patients with malaria complications. However, there are no current treatments that directly dislodge sequestered parasites from the microvasculature. We show that four common antiplasmodial drugs do not disperse rosettes...

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Autores:

Tipo de recurso:

Fecha de publicación:

2016

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/21912

Acceso en línea:

https://doi.org/10.1038/srep29317
https://repository.urosario.edu.co/handle/10336/21912

Palabra clave:

Plasmodium falciparum
Animals
Antimalarials
Artemisinins
Drug Discovery
Drug Resistance
Erythrocytes
High-Throughput Screening Assays
Microcirculation
Microvessels
Parasite Load
Plasmodium falciparum
Pyridines
Incidencia & prevención de la enfermedad

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