Discovery of novel heart rate-associated loci using the Exome Chip

Resting heart rate is a heritable trait, and an increase in heart rate is associated with increased mortality risk. Genome-wide association study analyses have found loci associated with resting heart rate, at the time of our study these loci explained 0.9% of the variation. This study aims to disco...

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Autores:

Tipo de recurso:

Fecha de publicación:

2017

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/24641

Acceso en línea:

https://doi.org/10.1093/hmg/ddx113
https://repository.urosario.edu.co/handle/10336/24641

Palabra clave:

Adult
Alleles
European Continental Ancestry Group
Exome
Female
Gene Frequency
Genetic Loci
Genetic Predisposition to Disease
Genome-Wide Association Study
Genotype
Heart Rate
Humans
Male
Middle Aged
Oligonucleotide Array Sequence Analysis
Polymorphism
Single Nucleotide
Risk Factors

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