Metabolic activity: A novel indicator of neuronal survival in the murine dopaminergic cell line CAD

Apoptosis is implicated in many neurodegenerative diseases, including Parkinson's disease (PD). Neuroprotective strategies targeting apoptosis need to preserve functional integrity of the saved cells to be effective. The aim of the present study was to evaluate a novel approach for analyzing ne...

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Autores:

Tipo de recurso:

Fecha de publicación:

2005

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/22406

Acceso en línea:

https://doi.org/10.1385/JMN:27:01:65
https://repository.urosario.edu.co/handle/10336/22406

Palabra clave:

Biological marker
Carbachol
Caspase inhibitor
Ceramide
Muscarinic receptor
Neurotrophic factor
Neurotrophin 3
Sphingosine derivative
Animal cell
Apoptosis
Article
Brain function
Catecholamine nerve cell
Cell activity
Cell death
Cell function
Cell line
Cell metabolism
Cell survival
Cell viability
Central nervous system
Dopaminergic nerve cell
In vitro study
Metabolic activation
Molecular model
Mouse
Nerve cell
Nonhuman
Parkinson disease
Receptor upregulation
Amino acid chloromethyl ketones
Animals
Apoptosis
Caspases
Cell line
Cell survival
Cysteine proteinase inhibitors
Dopamine
Energy metabolism
Mice
Neurons
Neuroprotective agents
Neurotrophin 3
Sphingosine
Murinae
Cad
Caspase inhibitor
Catecholaminergic cells
Ceramide
Metabolic activity
Microphysiometer
Neuronal apoptosis
Neurotrophin-3

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