Effects of moringa oleifera on glycaemia and insulin levels: A review of animal and human studies

Diabetes and related neurological complications are serious worldwide public health problems. The increasing number of affected individuals make it necessary to implement novel nutritional and therapeutic interventions. The tree Moringa oleifera (MO) has been used as a food source and for traditiona...

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Autores:
Tipo de recurso:
Fecha de publicación:
2019
Institución:
Universidad del Rosario
Repositorio:
Repositorio EdocUR - U. Rosario
Idioma:
eng
OAI Identifier:
oai:repository.urosario.edu.co:10336/22694
Acceso en línea:
https://doi.org/10.3390/nu11122907
https://repository.urosario.edu.co/handle/10336/22694
Palabra clave:
Ascorbic acid
Catalase
Cholesterol
Glucose
Glutathione
Glutathione peroxidase
Hemoglobin a1c
High density lipoprotein
Immunoglobulin a
Immunoglobulin g
Insulin
Interleukin 6
Low density lipoprotein
Malonaldehyde
Moringa oleifera extract
Nitrogen
Retinol
Superoxide dismutase
Triacylglycerol
Urea
Uric acid
Very low density lipoprotein
Antidiabetic activity
Antiinflammatory activity
Antioxidant activity
Clinical trial (topic)
Diabetes mellitus
Glucose blood level
Glucose intolerance
Glucose metabolism
Human
Hypolipidemic activity
Insulin blood level
Intestine flora
Lipid peroxidation
Moringa oleifera
Nonhuman
Postmenopause
Review
Diabetes
Insulin
Metabolism
Moringa oleifera
Rights
License
Abierto (Texto Completo)
Description
Summary:Diabetes and related neurological complications are serious worldwide public health problems. The increasing number of affected individuals make it necessary to implement novel nutritional and therapeutic interventions. The tree Moringa oleifera (MO) has been used as a food source and for traditional medicine purposes due to possible antihyperglycemic, antioxidant, anti-inflammatory, and lipid regulating properties. These properties may be explained by the presence of numerous phytochemicals in the leaves, fruits, roots and, oil of the tree. The evidence for acute antihyperglycemic effects of MO extract on diabetic animal models seems to be robust, but more chronic and long-term studies are needed. In contrast, the hypoglycemic effects of MO on humans are not as clear. The scarce number of human studies, together with a diverse range of methodologies and MO doses, may explain this. In addition, evidence regarding changes in insulin levels due to MO intervention is ambiguous, both in animal and human studies. Therefore, more structured studies are needed to clarify if MO has an effect on insulin levels or activity. © 2019 by the authors. Licensee MDPI, Basel, Switzerland.