Immunization with hepatitis B vaccine accelerates SLE-like disease in a murine model

Hepatitis-B vaccine (HBVv) can prevent HBV-infection and associated liver diseases. However, concerns regarding its safety, particularly among patients with autoimmune diseases (i.e. SLE) were raised. Moreover, the aluminum adjuvant in HBVv was related to immune mediated adverse events. Therefore, w...

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Autores:

Tipo de recurso:

Fecha de publicación:

2014

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/22257

Acceso en línea:

https://doi.org/10.1016/j.jaut.2014.06.006
https://repository.urosario.edu.co/handle/10336/22257

Palabra clave:

Aluminum hydroxide
Double stranded dna antibody
Hepatitis b surface antigen
Immunological adjuvant
Phosphate buffered saline
Recombinant hepatitis b vaccine
Antinuclear antibody
Hepatitis b vaccine
Animal experiment
Animal model
Animal tissue
Antibody titer
Anxiety
Article
Autoimmune disease
Blood cell count
Brain histology
Brain region
Cell lineage
Cognition
Controlled study
Disease exacerbation
Drug safety
Erythrocyte
Female
Forced swim test
Gliosis
Immunization
Kidney disease
Lupus like syndrome
Memory disorder
Microglia
Mouse
Nonhuman
Novel object recognition test
Proteinuria
Staircase test
Systemic lupus erythematosus
Y-maze test
Animal
Brain
Disease model
Drug effects
Immunology
Lupus erythematosus nephritis
Pathology
Pathophysiology
Animals
Brain
Cognition
Female
Hepatitis b vaccines
Lupus nephritis
Mice
Proteinuria
Autoimmune/autoinflammatory syndrome induced by adjuvant (asia)
Autoimmunity
Hepatitis b vaccine
Neuro-cognitive tests
Sle
Vaccination
animal
antinuclear
Antibodies
Disease models

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