The impact of HIV-1 within-host evolution on transmission dynamics

The adaptive potential of HIV-1 is a vital mechanism to evade host immune responses and antiviral treatment. However, high evolutionary rates during persistent infection can impair transmission efficiency and alter disease progression in the new host, resulting in a delicate trade-off between within...

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Autores:

Tipo de recurso:

Fecha de publicación:

2018

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/23826

Acceso en línea:

https://doi.org/10.1016/j.coviro.2017.12.001
https://repository.urosario.edu.co/handle/10336/23826

Palabra clave:

Chemokine receptor CCR5
Chemokine receptor CXCR4
Bottleneck population
CD4 lymphocyte count
Disease course
Genetic distance
Genetic variability
Host pathogen interaction
Human
Human immunodeficiency virus 1
Molecular epidemiology
Molecular evolution
Nonhuman
Phylogeny
Priority journal
Review
Viral genetics
Virus load
Virus morphology
Virus transmission
Virus virulence
Epidemic
Genetics
Host pathogen interaction
Human immunodeficiency virus 1
Human immunodeficiency virus infection
Molecular evolution
Pathogenicity
Theoretical model
Transmission
Virulence
Epidemics
HIV Infections
HIV-1
Host-Pathogen Interactions
Humans
Virulence
Molecular
Theoretical
Evolution
Models

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