ETP-46321, a dual p110?/? class IA phosphoinositide 3-kinase inhibitor modulates T lymphocyte activation and collagen-induced arthritis

Class IA phosphoinositide 3-kinases (PI3Ks) are essential to function of normal and tumor cells, and to modulate immune responses. T lymphocytes express high levels of p110? and p110? class IA PI3K. Whereas the functioning of PI3K p110? in immune and autoimmune reactions is well established, the rol...

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Autores:

Tipo de recurso:

Fecha de publicación:

2016

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/26038

Acceso en línea:

https://doi.org/10.1016/j.bcp.2016.02.005
https://repository.urosario.edu.co/handle/10336/26038

Palabra clave:

T lymphocytes
CD28
ICOS
Phosphatidyl inositol-3 kinase
PI3K inhibitors
Rheumatoid arthritis

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