Protection against malaria is conferred by passive transferring rabbit F(ab)2' antibody fragments, induced by Plasmodium falciparum MSP-1 site-directed designed pseudopeptide-BSA conjugates assessed in a rodent model

F(ab)2'-immunoglobulin (Ig) fragments induced by site-directed designed immunogens are emerging as novel tools of potential utility in the treatment of clinical episodes of transmissible diseases such as malaria. Immunogens based on reduced amide pseudopeptides based on site-directed molecular...

Full description

Autores:

Tipo de recurso:

Fecha de publicación:

2011

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/22617

Acceso en línea:

https://doi.org/10.1016/j.molimm.2010.11.007
https://repository.urosario.edu.co/handle/10336/22617

Palabra clave:

Bovine serum albumin
Glycyltyrosylserylleucylphenylalanylglutaminyllysylglutamyllysylmethionylvalineleucylasparaginylglutamylglycylthreonylserylglycylthreonylalaninamide
Immunoglobulin f(ab')2 fragment
Peptide vaccine
Polyclonal antibody
Pseudopeptide
Unclassified drug
Amino terminal sequence
Animal experiment
Animal model
Animal tissue
Article
Controlled study
Female
In vivo study
Malaria
Malaria control
Mouse
Nonhuman
Parasitemia
Passive immunization
Plasmodium falciparum
Priority journal
Protein analysis
Amino acid sequence
Animals
Cattle
Computational biology
Immunoglobulin fab fragments
Malaria
Merozoite surface protein 1
Mice
Molecular sequence data
Peptides
Plasmodium falciparum
Plasmodium yoelii
Rabbits
Mus
Oryctolagus cuniculus
Plasmodium falciparum
Plasmodium yoelii
Rodentia
Antibody-(fab)'2
Immunotherapy
Neutralizing antibody
Rodent malaria model
Synthetic vaccine
bovine
animal
passive
inbred balb c
protozoan
secondary
site-directed
neutralizing
Antibodies
Antibodies
Disease models
Immunization
Mice
Mutagenesis
Protein structure
Serum albumin

Rights

License

Abierto (Texto Completo)