Role of RUNX2 transcription factor in epithelial mesenchymal transition in non-small cell lung cancer lung cancer: Epigenetic control of the RUNX2 P1 promoter

Lung cancer has a high mortality rate in men and women worldwide. Approximately 15% of diagnosed patients with this type of cancer do not exceed the 5-year survival rate. Unfortunately, diagnosis is established in advanced stages, where other tissues or organs can be affected. In recent years, linea...

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Autores:

Tipo de recurso:

Fecha de publicación:

2019

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/23401

Acceso en línea:

https://doi.org/10.1177/1010428319851014
https://repository.urosario.edu.co/handle/10336/23401

Palabra clave:

COMPASS LIKE complex
Enzyme
Histone H3
Messenger RNA
MLL2 protein
MLL4 protein
Transcription factor RUNX2
Transcription factor Snail1
Transforming growth factor beta
Twist related protein 1
Unclassified drug
UTX protein
Vimentin
WDR5 protein
RUNX2 protein, human
Transcription factor RUNX2
Tumor marker
A-549 cell line
Adult
Aged
Article
Cancer growth
Cell migration
Clinical article
Controlled study
Correlation analysis
Enrichment culture
Epigenetics
Epithelial mesenchymal transition
Female
Gene control
Gene function
Gene knockdown
Gene loss
Gene overexpression
Genetic association
Human
Human cell
Human tissue
Lung adenocarcinoma cell line
Lung carcinogenesis
Lung metastasis
Male
Middle aged
Non small cell lung cancer
P57 gene
Priority journal
Promoter region
RUNX2 gene
SNAIL1 gene
Transcription regulation
TWIST1 gene
Very elderly
VIMENTIN gene
Apoptosis
Case control study
Cell motion
Cell proliferation
Follow up
Gene expression regulation
Genetic epigenesis
Genetics
Lung tumor
Metabolism
Non small cell lung cancer
Pathology
Prognosis
Secondary
Tumor cell culture
Tumor invasion
Adult
Aged
Aged, 80 and over
Apoptosis
Biomarkers, Tumor
Carcinoma, Non-Small-Cell Lung
Case-Control Studies
Cell Movement
Cell Proliferation
Core Binding Factor Alpha 1 Subunit
Epigenesis, Genetic
Epithelial-Mesenchymal Transition
Female
Follow-Up Studies
Gene Expression Regulation, Neoplastic
Humans
Lung Neoplasms
Male
Middle Aged
Neoplasm Invasiveness
Prognosis
Promoter Regions, Genetic
Tumor Cells, Cultured
Epigenetic
Epithelial mesenchymal transition
Histone
Lung cancer
RUNX2

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