A TGF-? mediated regulatory mechanism modulates the T cell immune response to rotavirus in adults but not in children

Children with acute RV-gastroenteritis (GE) had low or undetectable levels of circulating IFN-?+, IL-13+, IL-2+, IL-10+ or IL-17+ RV-T cells. IFN-?+ T cells and low frequencies of IL-10+ and IL-2+ CD4+ T cells were found in adults with RV-GE during acute and convalescence phases, respectively. Circu...

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Tipo de recurso:

Fecha de publicación:

2010

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/27853

Acceso en línea:

https://doi.org/10.1016/j.virol.2009.12.016
https://repository.urosario.edu.co/handle/10336/27853

Palabra clave:

Rotavirus
Humans
Interferon-gamma
Interleukin 13
Interleukin-2
Interleukin-10
Interleukin-17
Transforming growth factor betaT-lymphocytes
T-lymphocytes
regulatory

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