A New Approach to Obtaining N ?-t-Boc-Amino Acid Aldehydes from Asparagine and Glutamine for Reduced Amide Pseudopeptide Solid-Phase Synthesis

Reduced amide pseudopeptides have been proposed as structural probes that could be useful as potential malarial vaccine components. However, designing determined pseudopeptide sequences containing isoster peptide bonds, either on an asparagine (Asn) or on a glutamine (Gln) residues, can become diffi...