Concordance of CCR5 genotypes that influence cell-mediated immunity and HIV-1 disease progression rates

We used cutaneous delayed-type hypersensitivity responses, a powerful in vivo measure of cell-mediated immunity, to evaluate the relationships among cell-mediated immunity, AIDS, and polymorphisms in CCR5, the HIV-1 coreceptor. There was high concordance between CCR5 polymorphisms and haplotype pair...

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Autores:

Tipo de recurso:

Fecha de publicación:

2011

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/22375

Acceso en línea:

https://doi.org/10.1093/infdis/jiq023
https://repository.urosario.edu.co/handle/10336/22375

Palabra clave:

Chemokine receptor CCR5
Virus receptor
Acquired immune deficiency syndrome
Adult
AIDS patient
Allele
Article
Cellular immunity
Cohort analysis
Controlled study
Delayed hypersensitivity
Disease course
Female
Gene expression
Genetic association
Genetic transcription
Genotype
Haplotype
Heterozygosity
Human
Human immunodeficiency virus 1
Human immunodeficiency virus 1 infection
Human immunodeficiency virus infected patient
Immunoregulation
In vivo study
Major clinical study
Male
Nucleotide sequence
Phenotype
Priority journal
Single nucleotide polymorphism
Virus immunity
Virus pathogenesis
Virus replication
Adult
Disease Progression
Female
Genotype
Haplotypes
HIV Infections
HIV-1
Humans
Male
Genetic
Delayed
Cellular
CCR5
Hypersensitivity
Immunity
Polymorphism
Receptors

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