PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

Electrocardiographic PR interval measures atrio-ventricular depolarization and conduction, and abnormal PR interval is a risk factor for atrial fibrillation and heart block. Our genome-wide association study of over 92,000 European-descent individuals identifies 44 PR interval loci (34 novel). Exami...

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Autores:

Tipo de recurso:

Fecha de publicación:

2018

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/20449

Acceso en línea:

https://repository.urosario.edu.co/handle/10336/20449

Palabra clave:

Ion Channel
Transcription Factor
Disequilibrium
Genetic Analysis
Genome
Meta-Analysis
Risk Factor
African
Atrial Fibrillation
Atrioventricular Conduction
Cell Junction
Electric Activity
European
Gene Linkage Disequilibrium
Gene Locus
Genome-Wide Association Study
Heart Block
Heart Depolarization
Heart Rate
Human
Missense Mutation
Phenotype
Pr Interval
Qrs Interval
Signal Transduction
Canal de iones
Factor de transcripción
Sangre
Sistema cardiovascular
Enfermedades
Cardiovascular system
Blood
Heart Disease
Article
Enfermedades cardiovasculares
Fibrilación auricular
Bloqueo cardíaco

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