Using next-generation sequencing for characterising HLA-DRB1 and DQB1 loci in a cohort of Colombian women

The Colombian population is characterised by a high genetic diversity, secondary to the ethnic mixture arising from colonisation. Unfortunately, few reports are available regarding HLA-DRB1 and DQB1 diversity in Colombia to date. HLA-DRB1 and DQB1 diversity was identified in this study using next-ge...

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Autores:

Tipo de recurso:

Fecha de publicación:

2019

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/24212

Acceso en línea:

https://doi.org/10.1111/tan.13672
https://repository.urosario.edu.co/handle/10336/24212

Palabra clave:

HLA DQB1 antigen
HLA DRB1 antigen
Adult
Article
Cohort analysis
Colombian
Expectation-maximization algorithm
Female
Gene frequency
Gene linkage disequilibrium
Gene locus
Genetic variability
Haplotype
HLA system
HLA typing
Human
Major clinical study
Multicenter study
Next generation sequencing
Papillomavirus infection
Priority journal
Uterine cervix
Colombia
DQB1
DRB1
Human leukocyte antigen
Next-generation sequencing

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