Population genetics study of isoniazid resistance mutations and evolution of multidrug-resistant Mycobacterium tuberculosis

The molecular basis for isoniazid resistance in Mycobacterium tuberculosis is complex. Putative isoniazid resistance mutations have been identified in katG, ahpC, inhA, kasA, and ndh. However, small sample sizes and related potential biases in sample selection have precluded the development of stati...

Full description

Autores:

Tipo de recurso:

Fecha de publicación:

2006

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/22522

Acceso en línea:

https://doi.org/10.1128/AAC.00112-06
https://repository.urosario.edu.co/handle/10336/22522

Palabra clave:

Dna
Ethambutol
Isoniazid
Ahpc gene
Allele
Article
Gene
Gene identification
Gene interaction
Gene mutation
Human
Inha gene
Kasa gene
Katg gene
Molecular genetics
Multidrug resistance
Mycobacterium tuberculosis
Ndh gene
Nonhuman
Nucleotide sequence
Phenotype
Population genetics
Priority journal
Promoter region
Statistical analysis
Strain difference
Alleles
Antitubercular agents
Dna mutational analysis
Ethambutol
Evolution
Gene deletion
Humans
Isoniazid
Microbial sensitivity tests
Mutation
Mycobacterium tuberculosis
Open reading frames
Promoter regions (genetics)
Rifampin
Streptomycin
intergenic
multidrug-resistant
dna
bacterial
bacterial
antitubercular
single nucleotide
Antibiotics
Dna
Dna
Genes
Polymorphism
Sequence analysis
Tuberculosis

Rights

License

Abierto (Texto Completo)