Initial combination therapy with metformin plus colesevelam improves lipoprotein particles in patients with early type 2 diabetes mellitus

Background: The bile acid sequestrant colesevelam has been shown to significantly reduce low-density lipoprotein particle concentration (LDL-P) in adults with primary hyperlipidemia or type 2 diabetes mellitus (T2DM). Objective: To assess the effect of initial combination therapy with metformin plus...

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Autores:

Tipo de recurso:

Fecha de publicación:

2012

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/22299

Acceso en línea:

https://doi.org/10.1016/j.jacl.2012.05.005
https://repository.urosario.edu.co/handle/10336/22299

Palabra clave:

Apolipoprotein B
Chylomicron
Colesevelam
Hemoglobin a1c
High density lipoprotein cholesterol
Lipoprotein
Low density lipoprotein cholesterol
Metformin
Placebo
Triacylglycerol
Very low density lipoprotein
Adult
Article
Cholesterol blood level
Controlled study
Correlational study
Double blind procedure
Drug dose increase
Drug dose titration
Drug efficacy
Evening dosage
Female
Hemoglobin blood level
Human
Lipoprotein blood level
Major clinical study
Male
Morning dosage
Multicenter study
Non insulin dependent diabetes mellitus
Open study
Priority journal
Randomized controlled trial
Treatment duration
Triacylglycerol blood level
Adult
Allylamine
Anticholesteremic Agents
Apolipoprotein A-I
Apolipoproteins B
Double-Blind Method
Drug Administration Schedule
Female
Humans
Hyperlipidemias
Male
Metformin
Middle Aged
Placebo Effect
Triglycerides
Apolipoprotein
Bile acid sequestrant
Colesevelam
Lipoprotein particles
Low-density lipoprotein
Type 2 diabetes mellitus
Combination
Type 2
LDL
LDL
HDL
Glycosylated
Cholesterol
Cholesterol
Diabetes Mellitus
Drug Therapy
Hemoglobin A
Lipoproteins

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