Passive transfer of Plasmodium falciparum MSP-2 pseudopeptide-induced antibodies efficiently controlled parasitemia in Plasmodium berghei-infected mice

We have developed monoclonal antibodies directed against the pseudopeptide ?-130, derived from the highly conserved malarial antigen Plasmodium falciparum merozoite surface protein 2 (MSP-2), for obtaining novel molecular tools with potential applications in the control of malaria. Following isotype...

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Autores:

Tipo de recurso:

Fecha de publicación:

2009

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/22784

Acceso en línea:

https://doi.org/10.1016/j.peptides.2008.10.022
https://repository.urosario.edu.co/handle/10336/22784

Palabra clave:

Immunoglobulin
Immunoglobulin class
Malaria vaccine
Merozoite surface protein 2
Monoclonal antibody
Monoclonal antibody anti pseudopeptide psi 130
Pseudopeptide
Unclassified drug
Animal cell
Animal experiment
Animal model
Animal tissue
Article
Controlled study
Drug design
Drug mechanism
Drug synthesis
Female
Mouse
Nonhuman
Parasitemia
Passive immunization
Plasmodium berghei infection
Plasmodium falciparum
Priority journal
Animals
Antibodies, protozoan
Antigens, protozoan
Disease models, animal
Female
Immunization, passive
Malaria
Mice
Mice, inbred balb c
Parasitemia
Plasmodium berghei
Plasmodium falciparum
Protozoan proteins
Recombinant proteins
Murinae
Mus
Plasmodium berghei
Plasmodium falciparum
Anti-malarial vaccine
Ig isotype
In vivo neutralizing activity
Murine malarial infection
Pseudopeptide
protozoan

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