STAT4 but not TRAF1/C5 variants influence the risk of developing rheumatoid arthritis and systemic lupus erythematosus in Colombians

The aim of this study was to determine the influence of STAT4 (rs7574865) and TRAF1/C5 (rs10818488 and rs2900180) gene polymorphisms on the risk of developing rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) in a Colombian population. This was a case-control study in which 839 indivi...

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Autores:

Tipo de recurso:

Fecha de publicación:

2008

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/24142

Acceso en línea:

https://doi.org/10.1038/gene.2008.30
https://repository.urosario.edu.co/handle/10336/24142

Palabra clave:

Complement component C5
STAT4 protein
Tumor necrosis factor receptor associated factor 1
Article
Autoimmunity
Case control study
Colombia
Controlled study
Genetic polymorphism
Genetic risk
Genetic susceptibility
Genotype
Human
Major clinical study
Mouse strain
Polymerase chain reaction
Priority journal
Protein variant
Rheumatoid arthritis
Risk factor
Systemic lupus erythematosus
Alleles
Case-Control Studies
Cohort Studies
Colombia
Gene Frequency
Genotype
Humans
Risk Factors
STAT4 Transcription Factor
TNF Receptor-Associated Factor 1
Variation (Genetics)
Rheumatoid
Single Nucleotide
Systemic
Arthritis
Lupus Erythematosus
Polymorphism

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