Next generation sequencing in women affected by nonsyndromic premature ovarian failure displays new potential causative genes and mutations

Objective To identify new molecular actors involved in nonsyndromic premature ovarian failure (POF) etiology. Design This is a retrospective case-control cohort study. Setting University research group and IVF medical center. Patient(s) Twelve women affected by nonsyndromic POF. The control group in...

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Autores:

Tipo de recurso:

Fecha de publicación:

2015

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/24058

Acceso en línea:

https://doi.org/10.1016/j.fertnstert.2015.04.016
https://repository.urosario.edu.co/handle/10336/24058

Palabra clave:

Adamts19 gene
Adult
Article
Bioinformatics
Bmpr2 gene
Case control study
Cohort analysis
Computer model
Female
Gene
Gene mutation
Gene sequence
Human
Lhcgr gene
Major clinical study
Menopause
Next generation sequencing
Phenotype
Premature ovarian failure
Priority journal
Retrospective study
Sanger sequencing
Genetics
High throughput sequencing
Mutation
Primary ovarian insufficiency
Procedures
Sequence analysis
Adam protein
Bone morphogenetic protein receptor 2
Adam proteins
Adult
Case-control studies
Cohort studies
Female
High-throughput nucleotide sequencing
Humans
Mutation
Primary ovarian insufficiency
Retrospective studies
Sequence analysis
Adamts19
Bmpr2
Next generation sequencing
Pof
Premature ovarian failure
human
human
type ii
Adamts19 protein
Bmpr2 protein
Bone morphogenetic protein receptors

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