ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash and immunological manifestations in patients with systemic lupus erythematosus with European ancestry

Purpose: It was hypothesised that the coding variant (R77H), rs1143679, within ITGAM could predict specific clinical manifestations associated with systemic lupus erythematosus (SLE). Method: To assess genetic association, 2366 patients with SLE and 2931 unaffected controls with European ancestry we...

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Autores:

Tipo de recurso:

Fecha de publicación:

2010

Institución:

Universidad del Rosario

Repositorio:

Repositorio EdocUR - U. Rosario

Idioma:

eng

OAI Identifier:

oai:repository.urosario.edu.co:10336/22389

Acceso en línea:

https://doi.org/10.1136/ard.2009.120543
https://repository.urosario.edu.co/handle/10336/22389

Palabra clave:

CD11b antigen
ITGAM antigen
Unclassified drug
Autoantibody
CD11b antigen
Arthritis
Article
Cohort analysis
Controlled study
Discoid rash
Disease association
Europe
Gene frequency
Genetic variability
Hematologic disease
Human
Hypothesis
Immunopathology
Inflammation
Kidney disease
Major clinical study
Mouth ulcer
Nephritis
Neurologic disease
Photosensitivity
Priority journal
Rash
Risk assessment
Systemic lupus erythematosus
Blood
Discoid lupus erythematosus
Female
Genetic predisposition
Genetics
Genotype
Immunology
Lupus erythematosus nephritis
Male
Autoantibodies
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Humans
Lupus Nephritis
Male
Systemic
human
Discoid
CD11b
ITGAM protein
Antigens
Lupus Erythematosus
Lupus Erythematosus

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