Synthetic evaluation of standard and microwave-assisted solid phase peptide synthesis of a long chimeric peptide derived from four Plasmodium falciparum proteins
An 82-residue-long chimeric peptide was synthesised by solid phase peptide synthesis (SPPS), following the Fmoc protocol. Microwave (MW) radiation-assisted synthesis was compared to standard synthesis using low loading (0.20 mmol/g) of polyethylene glycol (PEG) resin. Similar synthetic difficulties...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2018
- Institución:
- Universidad del Rosario
- Repositorio:
- Repositorio EdocUR - U. Rosario
- Idioma:
- eng
- OAI Identifier:
- oai:repository.urosario.edu.co:10336/22628
- Acceso en línea:
- https://doi.org/10.3390/molecules23112877
https://repository.urosario.edu.co/handle/10336/22628
- Palabra clave:
- Peptide
Protozoal protein
Chemistry
Drug effect
Metabolism
Microwave radiation
Molecular weight
Plasmodium falciparum
Solid phase synthesis
Spectroscopy
Synthesis
Microwaves
Molecular weight
Peptides
Plasmodium falciparum
Protozoan proteins
Solid-phase synthesis techniques
Spectrum analysis
Chimeric peptide
Coupling
Fmoc protocol
Microwave radiation
Solid phase peptide synthesis
- Rights
- License
- Abierto (Texto Completo)