Hypothalamic-pituitary-adrenal axis dysfunction in streptozotocin(STZ)-diabetic rats: effect of lipoic acid and ?-tocopherol treatment

Background and aims: Glucocorticoid release is involved in glucose counterregulation, and a diminished or absent adrenocortical function renders non-diabetic as well as insulin-treated diabetic subjects prone to hypoglycemia. We previously demonstrated that STZ-diabetic rats show increased basal, bu...